In their midweek affair, Columbus were without Cesar Ruvalcaba Perez due to a sore ankle, Patrick Schulte was sidelined with a torso issue, Rudy Camacho had a thigh strain and Malte Amundsen was sidelined because of a knee injury.

Guatemala face Canada in the quarter-finals of the CONCACAF Gold Cup on Sunday, meaning Nicholas Hagen will miss this upcoming fixture for the Crew, while Max Arfsten is representing the USA on Sunday when they take on Costa Rica.

Canadian striker Jacen Russell-Rowe had a brace against the Five Stripes earlier this week, with the other Columbus goal coming courtesy of Andres Herrera.

Meanwhile, the Union did not have Olivier Mbaizo or Mikael Uhre available on Wednesday due to adductor strains, while Tai Baribo missed their midweek victory as he was stuck in Israel during the international window.

They will be without Quinn Sullivan and Nathan Harriel who are with the US at the Gold Cup, while Danley Jean Jacques and Andre Blake could both be back after Haiti and Jamaica were eliminated from that tournament.

Bruno Damiani converted a 10th-minute penalty for Philly against the Chicago Fire, while Andrew Rick collected a clean sheet, making two stops in the victory.

Columbus Crew possible starting lineup:

Bush; Moreira, Zawadzki, Cheberko; Herrera, Chambost, Nagbe, Jackson; Rossi, Gazdag; Russell-Rowe

Philadelphia Union possible starting lineup:

Blake; Bedoya, Glesnes, Makhanya, Wagner; Vassilev, Bueno, Lukic, Jacques; Damiani, Donovan