Manchester United:

Joshua Zirkze: Suffered a thigh injury during the match against Newcastle on April 14th. He is expected to miss the remaining games of the season.

Amad Diallo: Suffered an ankle injury on February 14th. He is expected to make a comeback around May 20th. Currently, he is still recovering from the ankle injury and training separately from the team.

Toby Collyer: Suffered a contusion on February 10th.

Lisandro Martínez: Suffered a knee sprain on February 3rd. He is expected to return on January 1st, 2026 and has already been ruled out for the rest of this season.

Matthijs de Ligt: Has missed the last three games of Manchester United due to a foot injury. He did not participate in Manchester United's open training on Wednesday morning and will miss the second leg of the match.

Jonny Evans: Suffered a back contusion. He has returned to training after being absent for four months, but it is uncertain whether he can play in the second leg of the match.

Eden Harwood: Suffered an ankle injury and has been absent for four weeks. He returned to the squad list in the match against Newcastle last Sunday, but suffered a "minor setback" and will not be able to play in the second leg of the match against Lyon.

Lyon:

Malik Fofana: Suffered a knee sprain. He is expected to make a comeback on April 26th. After being absent for a month, he has resumed training and is expected to be included in the squad list for this match.

Ernest Nuamah Appiah: Injured. He is expected to return on June 1st and has already been ruled out for the rest of this season.

Orel Mangala: Suffered a torn cruciate ligament. He is expected to return on November 29th.